Skip to main content

EBOLA VIRUS DISEASE


What is EBOLA VIRUS disease?


EBOLA VIRUS disease also known as Ebola Haemorrhagic fever is one of the most fatal and serious illness in this era.

The first transmission of the virus to humans was from animals and then it continued from one one human to the others.

The case fatality rate of this disease usually ranges from 25% to 90% in the past few outbreak, thus making it one of the most feared disease.
It first out broke in the remote areas of the Africa, but recently it has also spread to the urban areas of the Africa.

Ebola virus disease was noticed for the first time in 1976 in the village of Sudan. However, the recent breakout is on a massive level as it is causing a lot of deaths in the African countries like in Nigeria, Liberia, and Sierra Leone etc.

The family of this virus consists of three genera which are Cuevavirus, Marburgvirus, and Ebolavirus, Besides, there are five species that have been identified so far which are Cuevavirus, Marburgvirus, and Ebolavirus. The recent break out is cause by the Zaire species.

The fruit bats of the petropodidae family are thought to be the host of this virus. Ebola is transmitted to humans by having the close contact with the animals in the affected areas. After that transmission to humans is caused by the direst contact and transfer of the bodily secretions. Health care works are mostly affected as they are in direct contact with the Ebola Virus patients.

There are various symptoms of this disease. Some of them are fever, fatigue, pain in the muscles, headache and sore throat is also noticed in the patients. The most dangerous symptoms are vomiting, diarrhoea, impairment of the functions of kidney and liver which ultimately leads to both external and internal bleeding and very low white blood cell count.


As far as the treatment is concerned, there is not any specific treatment for the Ebola Virus disease. The treatment is to counter the symptoms of the patient. Researchers have been working on the potential vaccines for this onslaught. 

Comments

Popular posts from this blog

ANTI-MULLERIAN HORMONE AND FERTILITY

ANTI-MULLERIAN HORMONE AND FERTILITY Initially Anti-Mullerian hormone was only considered in its involvement in the sexual differentiation and Mullerian regression in the males, but now it serves as a bio-marker for the ovarian reserve. It expresses itself in the small antral follicles. It can predict the condition of the patients with assisted reproductive therapy and it is also important in the patients with the polycystic ovary. The following points elaborates the role of AMH in the fertility Anti-Mullerian hormone and its effect on fertility and infertility. ·          Anti – Mullerian hormone is a protein in its composition and is encoded by the help of the AMH gene. ·          It is produced by the granulose cells which are present in the ovarian cells. ·          It has a molecular weight of 140 KDa. ·          AMH which is also known as Mullerian-inhibiting substance is a member of the super family named as transforming growth factor-beta(TGF-β). This fa

6-MERCAPTOPURINE

Healthconcerns “Articles on cancer” is going to add a complete pharmacology and the medicinal chemistry of the Anti-cancer drugs. So here is the first one as “6-MERCAPTOPURINE” 6-Mercaptopurine Chemical structure Chemically 6-Mercaptopurine is analog of adenine and hypoxanthine                                                  Mechanism of action 6-Mercaptupurine is converted to   6- Mercaptopurine nucleosides leading to De novo inhibition of purine nucleotide synthesis. ¨       6-Mercaptopurine competes with hypoxanthine and guanine for the enzyme hypoxanthine/guanine phosphoribosyltransferase  and itself converted to thioinosinic acid                                                                      Inosinic acid (I) MP                                                                                  Thioinosinic acid (I MP)   ¨       TIMP inhibits several reactions involving inosinic mono phosphate (IMP) including its convers