healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY

healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY: Antibody Directed Enzyme Prodrug Therapy (ADEPT) Ehealthconcerns has brought again a new sensational technology for treating the ca...

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6-MERCAPTOPURINE

Healthconcerns “Articles on cancer” is going to add a complete pharmacology and the medicinal chemistry of the Anti-cancer drugs. So here is the first one as “6-MERCAPTOPURINE” 6-Mercaptopurine Chemical structure Chemically 6-Mercaptopurine is analog of adenine and hypoxanthine Mechanism of action 6-Mercaptupurine is converted to 6- Mercaptopurine nucleosides leading to De novo inhibition of purine nucleotide synthesis. ¨ 6-Mercaptopurine competes with hypoxanthine and guanine for the enzyme hypoxanthine/guanine phosphoribosyltransferase and itself converted to thioinosinic acid ...

Detection of bio-markers over the past decade"

Detection of bio-markers over the past decade" As we are fully aware of the fact that the development of the new bio-markers is of great significance in treating and preventing the diseases or the complex toxins outbreaks in the body, so scientist and researchers are always eager to find new bio-markers to prevent the onslaught of the diseases. First of all lets us know that what is a bio-marker? A bio-marker can be termed as characteristic that can play a very vital role in the reflection of the intensity of a disease in the body. It can also be used as a detector to indicate a disease in the body; it can be assessed by a particular antibody produced in response to that disease. Moreover, they also make us enable to initiate a therapy which can act only on the target site in the body to prevent the loss of the healthy cells and tissues in the body. Bio-markers can be classified as disease related and drug related bio-markers. Disease related bio-markers help us t...

ANTIBODY DIRECTED ENZYME PRODRUG THERAPY

Antibody Directed Enzyme Prodrug Therapy (ADEPT) Ehealthconcerns has brought again a new sensational technology for treating the cancer by the name of ADEPT under the heading of “ARTICLES ON CANCER” ADEPT is a new type of cancer treatment, drugs used called monoclonal antibodies | , ( Antibodies produced by a single cell) ( substances that can locate and bind to cancer cells wherever they are in the body) or antibodies made in the lab to lock onto specific antigens. Antigens are substances that can be recognized by the immune system. Monoclonal antibodies are used in chemotherapy and radioactive substances, to deliver cancer treatment directly to cancer cells, not healthy Monoclonal antibodies Monoclonal antibodies are used to try to destroy the cancer cells, while causing little harm to normal cells. They recognize the protein on the surface of the cancer cell and lock onto it. Some monoclonal antibodies can then trigger (activate) the body’s immun...

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