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healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY

healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY: Antibody Directed Enzyme Prodrug Therapy (ADEPT) Ehealthconcerns has brought again a new sensational technology for treating the ca...

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Obesity Linked with food in American Schools

Obesity Linked with food in American Schools By Mahvisha Kanwal What’s the issue?                               In USA, elementary and primary schools takes the responsibility of providing a free lunch facility to the students. Although all of the schools have maintained the quality of food, but according to a recent study, almost one third of all the children and youth are considered as over-weight. The basic cause of this issue is that, the nutritional value of food is not being kept in mind by the school community. Another issue of increasing rate of obesity is that the schools food department attract the children by making yummy fast food which is for sure not healthy for the children. That’s why children like to eat food from the school cafe rather to bring from home. According to WhatsForLunchNYC.com , a New York City-based ...

6-MERCAPTOPURINE

Healthconcerns “Articles on cancer” is going to add a complete pharmacology and the medicinal chemistry of the Anti-cancer drugs. So here is the first one as “6-MERCAPTOPURINE” 6-Mercaptopurine Chemical structure Chemically 6-Mercaptopurine is analog of adenine and hypoxanthine                                                  Mechanism of action 6-Mercaptupurine is converted to   6- Mercaptopurine nucleosides leading to De novo inhibition of purine nucleotide synthesis. ¨       6-Mercaptopurine competes with hypoxanthine and guanine for the enzyme hypoxanthine/guanine phosphoribosyltransferase  and itself converted to thioinosinic acid                                         ...

ANATOMY OF NEUROTRANSMITTERS

Anatomy of neurotransmitters An understanding of the synaptic transmission is of great importance in understanding the basic principle of chemical signaling between the neurons. This chemical process of interaction or signaling between the neurons occurs at the end of the axon, in a structure called synapse. Synapse: As neurons form a network, so they have to be interconnected for the purpose of transmission of nerve impulse from one neuron to the other. But, unlike other cells there is a lack of a cellular continuity between two neurons, as they have a space between them called as the synapse. The mechanism of chemical signaling involves the release of a chemical, called a neurotransmitter from a presynaptic neuron, which further binds to the receptors which are located in the postsynaptic neuron. These neurotransmitters then act on their particular receptors and produce a particular response. Neurotransmitters: Neurotransmitters are defined as endogenous chemicals i...