healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY

healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY: Antibody Directed Enzyme Prodrug Therapy (ADEPT) Ehealthconcerns has brought again a new sensational technology for treating the ca...

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6-MERCAPTOPURINE

Healthconcerns “Articles on cancer” is going to add a complete pharmacology and the medicinal chemistry of the Anti-cancer drugs. So here is the first one as “6-MERCAPTOPURINE” 6-Mercaptopurine Chemical structure Chemically 6-Mercaptopurine is analog of adenine and hypoxanthine Mechanism of action 6-Mercaptupurine is converted to 6- Mercaptopurine nucleosides leading to De novo inhibition of purine nucleotide synthesis. ¨ 6-Mercaptopurine competes with hypoxanthine and guanine for the enzyme hypoxanthine/guanine phosphoribosyltransferase and itself converted to thioinosinic acid ...

SIGNS AND SYMPTOMS OF DEPRESSION

Signs and symptoms of depression: Depression is one of the most spread diseases in the whole world. A lot of people are suffering from this disease due to the stress and certain other factors faced by them in the daily life. There are many signs and symptoms which can easily show that a person is in a depression mode. Some of the symptoms and the signs of the depression condition are as following, feeling blue, loosing interest in the usual activities, fatigue, headache, significant increase or decrease in the appetite, a gain or loss of the weight, a tendency to isolate from the friends and the family. Some of the important signs and the symptoms of the depression are listed as following, 1. Continuous sad and angry mood 2. Having feelings of hopelessness, pessimism 3. Loss of interest in the life and daily activities 4. ...

CASE SCENARIO OF A SMOKER

Tobacco use mostly involves the burning tobacco in the form and cigarette and then inhaling the tobacco. Many smokers begin smoking during the early stages of their lives, like when they are in their teens. There are many reasons to start smoking tobacco at such an early stage of their lives, such as psychological and socio-economic pressures from their surroundings, bad company, and lack of proper guidance by their guardians. After sometime, these habits become permanent due to the avoidance of the withdrawal symptoms and the dependence on the intake of nicotine. The adverse effects associated with smoking problems are responsible for more than 400,000 ore almost one out of every five deaths in a country like United States of America. Smoking along with a poor diet and the absence of physical activity can lead to various serious complications which can be related to health and also affecting the people around you. Although, smoking alone is really deleterious to the healt...

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