healthconcerns

Healthconcerns “Articles on cancer” is going to add a complete pharmacology and the medicinal chemistry of the Anti-cancer drugs. So here is the first one as “6-MERCAPTOPURINE” 6-Mercaptopurine Chemical structure Chemically 6-Mercaptopurine is analog of adenine and hypoxanthine                                                  Mechanism of action 6-Mercaptupurine is converted to   6- Mercaptopurine nucleosides leading to De novo inhibition of purine nucleotide synthesis. ¨       6-Mercaptopurine competes with hypoxanthine and guanine for the enzyme hypoxanthine/guanine phosphoribosyltransferase  and itself converted to thioinosinic acid                                         ...

healthconcerns: ANTIBODY DIRECTED ENZYME PRODRUG THERAPY : Antibody Directed Enzyme Prodrug Therapy (ADEPT) Ehealthconcerns has brought again a new sensational technology for treating the ca...

  Antibody Directed Enzyme Prodrug Therapy (ADEPT) Ehealthconcerns has brought again a new sensational technology for treating the cancer by the name of ADEPT under the heading of “ARTICLES ON CANCER” ADEPT is a new type of cancer treatment,   drugs used called monoclonal antibodies | , ( Antibodies produced by a single cell) ( substances that can locate and bind to cancer cells wherever they are in the body) or antibodies made in the lab to lock onto specific antigens. Antigens are substances that can be recognized by the immune system. Monoclonal antibodies are used in chemotherapy and radioactive substances, to deliver cancer treatment directly to cancer cells, not healthy Monoclonal antibodies Monoclonal antibodies are used to try to destroy the cancer cells, while causing little harm to normal cells. They recognize the protein on the surface of the cancer cell and lock onto it. Some monoclonal antibodies can then trigger (activate) the body’s immun...